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Glossary

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WOMAN II Consortium
Last Review: 21/02/2003

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Calcitonin: a hormone produced by the parathyroid, thyroid and thymus glands and responsible for increasing the amount of calcium and phosphate deposited on bones.

Climacteric: it is a period of life around the menopause which is characterised by the declining levels of sex hormones. It include the premenopausal and the early postmenopausal period.

Cardiovascular Disease: describes a group of diseases related to the heart and arteries, including coronary artery disease, stroke, hypertension (high blood pressure), and peripheral vascular disease (atherosclerosis or "hardening of the arteries").

Constipation: stipsi.

Dysmenorrea: menstrual pain.

Dyspareunia: pain during sexual intercourse.

Dysuria: pain during urination.

Endometrium: the lining of the uterus shed with each period.

Fluctuations in sexual desire (loss of libido): for some women the loss is so great that they actually find sex repulsive, in much the same way as they felt before puberty. What hormones give, loss of hormones can take away. See also vaginal atrophy.

FSH: Follicle Stimulating Hormone produced by hypophysis.

Gonadotrophins: a collective term for follicle stimulating hormone (FSH) and lutenising hormone (LH).

Hormone: a hormone is a substance that is produced in one part of the body, passes into the bloodstream and is carried to other distant organs or tissues where it acts to modify their structure of function.

Hot Flushes: uncomfortable waves of heat (sudden warm feeling, with blushing) that involve all the body's in response to declining of estrogen levels. It's still unknown why hot flashes last only a few months for some women, and persist for years or never occur at all for others. During a hot flash, which typically lasts from 1 to 5 minutes, the heart beats faster, and blood vessels dilate causing a flush. Women may also sweat or suffer a wave of anxiety.

HT: hormone therapy.

Incontinence: involuntary leaking of urine such as when coughing or sneezing. It is correlated with the decline of estrogens levels and reflects a general loss of smooth muscle tone.

Induced Menopause: is a menopause due to one of a number of medical interventions. Surgically removing both ovaries (bilateral oophorectomy) before natural menopause causes surgical menopause. Induced menopause can also occur if the ovaries are rendered inactive by pelvic radiation, chemotherapy, or certain other drugs. Due to their abrupt loss of ovarian hormones, women who experience induced menopause are more likely to have a sudden onset of hot flashes and other menopause-related disturbances such as a dry vagina. These women, as well as women who experience early natural menopause (before age 40) or prolonged time without menstrual periods due to excessive exercising or dieting, may be at greater risk later in life for health problems such as osteoporosis (thinning of bones) and heart disease since they spend more years without the protective effect of estrogen. A woman who has a hysterectomy (uterus removed but not the ovaries) prior to experiencing natural menopause usually continues to produce hormones and thus will not experience surgical menopause. However, sometimes removal of the uterus may interrupt the blood supply to the ovaries. In this unusual circumstance, a woman may experience earlier menopause-related changes.

Mammography: mammography is a special type of x-ray imaging used to create detailed images of the breast. an x-ray of the breast.

Mastectomy: surgery to remove the breast.

Menarche: first menstruation.

Menopause: is a natural occurrence in a woman's life that designates the end of fertility. Strictly speaking, menopause is a woman's very last menstrual period. However, it's also the transition period in a woman's life that begins as her body starts to slow its production of estrogen. This reduction in the amount of estrogen in the body can have wide ranging effects from short-term symptoms such as hot flashes, night sweats, and vaginal dryness, to an increased risk of osteoporosis. Menopause results from the ovaries being depleted of their supply of eggs, leading to a decrease in the production of the sex hormones: estrogen, progesterone, and testosterone. Most women can tell if they are approaching menopause when their menstrual periods start changing. "Perimenopause" and "the menopause transition" are terms used to describe this time. Menopause is confirmed when a woman has not had a menstrual period for 12 consecutive months (and no other biologic or physiologic cause can be identified for lack of periods). Until twelve consecutive months have passed without a period, a midlife woman may still be able to get pregnant.

Osteoporosis (thinning of the bones): a disease which causes bones to lose mass and become porous and brittle. Frequently leads to fractured spine, wrists or hips in elderly women.

Parity: number of pregnancy.

Postmenopausal blues, mood swings: In the past, just about every emotional blip or bout of the blues felt by women in their 40s or 50s was attributed to menopause. Women can become irritable when hot flashes rob them of a good night's sleep, but there is no correlation between menopause and serious depression. Since depression affects one woman in four at some point in life, however, persistent low moods should never be ignored. Other symptoms of depression include insomnia (or sleeping too much), loss of appetite (or eating too much), and feeling helpless, hopeless or worthless. If you experience these symptoms, be sure to talk to your health care provider.

Stress Incontinence: involontary loss of urine due to an effort.

Stress / Urge Incontinence: involontary loss of urine due to an effort and impossibility to delay the urination.

Timing of Menopause: In the Western world, the majority of women experience natural menopause on average at about age 51, but it can occur as early as in a woman's 30s and, rarely, as late as in her 60s. Contrary to previous opinion, there is no correlation between the time of a woman's first period and her age at menopause. In addition, age at menopause is not influenced by race, height, the number of children a woman has had, or whether she took oral contraceptives for birth control. However, cigarette smoking can influence the age of menopause; smokers and even former smokers can reach menopause two years earlier than nonsmokers.

Urge Incontinence: impossibility to delay the urination.

Vaginal atrophy, Vaginal dryness: a condition which causes the lining of the vagina to become dry and lose its elasticity. Can also cause urinary tract infections. Often results in painful intercourse.
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Last Update: 21/08/2003